Which instruction helps a patient alleviate discomfort after administering eye drops?

Maintaining pressure on the lacrimal duct after administering eye drops is a crucial step for several reasons. This technique helps prevent the medication from draining into the tear duct system, which can otherwise lead to systemic absorption of the drug and decrease its effectiveness on the eye. By applying pressure to the lacrimal duct for about one to two minutes, patients can also minimize any potential discomfort or irritation that may arise from excess drops entering the nasal cavity or throat. This instruction is especially important for certain medications, as it can enhance their action by allowing more time for absorption in the eye itself.

Washing hands before and after administering eye drops is essential for hygiene, but it does not directly address discomfort. Closing the eyes tightly can actually increase discomfort by creating pressure rather than allowing the medication to spread evenly across the surface of the eye. Blinking immediately after instillation may not provide sufficient time for the medication to be properly absorbed before being washed away. Therefore, maintaining pressure on the lacrimal duct stands out as the most effective instruction for alleviating discomfort and ensuring the medication's efficacy.